3-Ethoxycarbonyl-2-hydroxy-6-methoxy-4-methylbenzoic acid
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چکیده
منابع مشابه
SYNTHESIS OF 8-HYDROXY-6-METHOXY- 3-UNDECYLISOCOUMARIN AND 2-HY DROXY - 4-METHOXY-6-(2-OXOTRIDECYL) BENZOIC ACID
Straightforward conversion of (+)-6,8-dimethoxy-3,4-dihydro-3- undecylisocoumarin (3) to the title isocoumarin was carried out. Hydrolytic ring opening of (3) afforded the hydroxy acid (4) which was immediately oxidized to keto acid (5) using chromic acid, Cyclodehydration of (5) afforded the 6,8- dimethoxy-3-undecylisocoumarin (6) which on selective demethylation of 8- methoxy group furni...
متن کاملsynthesis of 8-hydroxy-6-methoxy- 3-undecylisocoumarin and 2-hy droxy - 4-methoxy-6-(2-oxotridecyl) benzoic acid
straightforward conversion of (+)-6,8-dimethoxy-3,4-dihydro-3- undecylisocoumarin (3) to the title isocoumarin was carried out. hydrolytic ring opening of (3) afforded the hydroxy acid (4) which was immediately oxidized to keto acid (5) using chromic acid, cyclodehydration of (5) afforded the 6,8- dimethoxy-3-undecylisocoumarin (6) which on selective demethylation of 8- methoxy group furnished ...
متن کاملCrystal structures of 4-methoxy-6-methyl- and 4-hydroxy-6-methyl-2-pyrones.
interesting results because of the regular arrangement of the molecules in the environment.1–3 We previously reported on the photocycloaddition reaction of 4-methoxy-6-methyl-2-pyrone (1a) (Fig. 1) with maleimide (2) in the solid state to give a highly stereoselective [2 + 2] cycloadduct4 owing to the formation of two sets of 1:1 complex crystals between (1a) and (2) (Fig. 1).5 The crystal show...
متن کامل6-[(4′-Ethoxycarbonyl-[1,1′-biphenyl]-4-yl)oxy]hexanoic acid
In the title compound, C21H24O5, the dihedral angle between the benzene rings is 19.57 (15)°. In the crystal, the mol-ecular arrangement makes up head-to-head centrosymmetric dimers assembled by pairs of O-H⋯O bonds; this arrangement builds a graph-set ring motif of R (2) 2(8). The dimers are linked into a tape running along the b-axis direction through C-H⋯O inter-actions. The packing is furth...
متن کاملSynthesis of gefitinib from methyl 3-hydroxy-4-methoxy-benzoate.
This paper reports a novel synthesis of gefitinib starting from methyl 3-hydroxy-4-methoxybenzoate. The process starts with alkylation of the starting material, followed by nitration, reduction, cyclization, chlorination and two successive amination reactions. The intermediates and target molecule were characterized by 1H-NMR, 13C-NMR, MS and the purities of all these compounds were determined ...
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ژورنال
عنوان ژورنال: Acta Crystallographica Section E Structure Reports Online
سال: 2012
ISSN: 1600-5368
DOI: 10.1107/s1600536812015012